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The MaxRecovery™ BiooPure™ RNA Isolation Reagent is a single-phase reagent for extraction of total RNA or enriched small RNA (including miRNA) from solid tissues, cultured cells, and cell-free fluids such as serum and plasma. The BiooPure reagent contains guanidinium, a powerful chaotropic agent effective for rapidly inactivating nucleases, and phenol, an organic solvent used to denature and separate proteins and DNA from RNA.
Selected Citations:
Burgos K, Javaherian A, Bomprezzi R. et al.(2013) Identification of extracellular miRNA in human cerebrospinal fluid by next-generation sequencing. RNA Journal. (5):712-22. doi: 10.1261/rna.036863.112.
Shende V.R., Goldrick M.M., Ramani S. and Earnest D.J. (July 22, 2010) Expression and Rhythmic Modulation of Circulating MicroRNAs Targeting the Clock Gene Bmal1 in Mice. PLoS ONE 6(7): e22586. doi:10.1371/journal.pone.0022586
Nakashe, P. et al. (2011) Adapter Dimer Reduction in High-Throughput microRNA Profiling. OMICS 1(1): 6-11. http://www.asciencejournal.net/asj/index.php/OMICS/article/view/290/245
Xu SJ, Zhang R, et al. (2012) Oxidative Stress Mediated-Alterations of the MicroRNA Expression Profile in Mouse Hippocampal Neurons. International Journal of Molecular Sciences. doi:10.3390/ijms131216945
Zhang, J. et al. (2012) FRS2α-Mediated FGF Signals Suppress Premature Differentiation of Cardiac Stem Cells Through Regulating Autophagy Activity. Circulation Research. doi: 10.1161/CIRCRESAHA.111.255950
Zhang CZ, Liu L, Cai M, Pan Y, Fu J, et al. (2012) Low SIRT3 Expression Correlates with Poor Differentiation and Unfavorable Prognosis in Primary Hepatocellular Carcinoma. PLoS ONE 7(12): e51703. doi:10.1371/journal.pone.0051703
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