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T3™ Conjugation Kit
For Targeted Delivery of siRNA
 
 
Catalog# Product Name Quantity US List Price
5150
T3™ Conjugation Kit for Ab < 75 kDa
15 - 20 injections $1495
5151
T3™ Conjugation Kit for Ab ≥ 75 kDa
15 - 20 injections $1495
 
 
   Benefits  
· Offers targeted in vivo or in vitro delivery of siRNA or miRNA
· Can be used to target almost any cell or tissue type
· Flexible – works with multiple RNAi agents and routes of delivery
· Use less siRNA
· Reduces off target effects
· Gentle and non-toxic
 
 
   Description  
One of the hurdles to delivering RNAi effectively includes being able to deliver siRNA into specific cells and organs. Using the T3™ Conjugation Kit, based on Bioo Scientific’s patent pending Targeted Transport Technology, scientists can administer siRNA to target cells and tissues using both in vivo and in vitro models.

The T3 Conjugation Kit lets scientists deliver siRNA or miRNA into any cell type they want by conjugating the T3 carrier to an antibody that is specific to a receptor or other extracellular domain specific to the cell or tissue type they want to target. The T3 procedure does not require any prior modifications of the antibody or the RNAi agent and can be performed in a few simple steps (see below).

T3™ Conjugation Kit Procedure

1. Identify an antibody that is specific to a receptor specific to your targeted cell type
2. Conjugate the antibody to the T3 Carrier
3. Load the T3 Conjugate with siRNA or miRNA
4. Administer to animal or transfect cell lines
5. T3 Conjugate is taken up by targeted cells
6. The siRNA or miRNA is released inside the targeted cells
 
 
   Key Features  
If you are planning on storing the kit for >1 month, we recommend storing the T3 Carrier in a -20ºC, frost-free freezer. The shelf life of the MaxCarrier T3 Conjugation Kit is 6 months when stored properly.

This kit is sufficient for 15 - 20 injections. The number of in vivo injections will vary depending on specificity of the user’s antibody, concentration of siRNA and target receptor population. Concentration optimization should be performed before each experiment.

Each kit can conjugate up to 3 mg of antibody
Each kit provides the reagents to make:
3 mg of one antibody conjugate, or
1 mg each of three different antibody conjugates, or
2 mg of one antibody conjugate and 1 mg of two other antibody conjugates
 
 
   Tags  
RNAi siRNA delivery
5150 5151
T3 Targeted delivery
 
 
   Notes  
All products sold by Bioo Scientific are intended for research use only unless otherwise indicated. This product is not intended for diagnostic or drug purposes, or for use in humans.
 
 
 
 
 
 
  Related Product/Services
Targeted in vivo siRNA Delivery Services
 
 
  Resources
Download 5150 T3 maunal
Download 5151 T3 manual
 

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