- Consistent, reproducible results
- High sensitivity – 50% B/Bo (< 1.0 ng/mL)
- Assay Range 0.1 ng/ml – 10 ng/ml
- Fast results – Less than 2 hours regardless of number of samples
The MaxSignal® Lidocaine ELISA Kit uses a competitive immunoassay method to determine the amount of lidocaine present in a blood or urine sample. Test plate wells are coated with drug. Blood or urine sample is added for analysis, along with antibody against lidocaine. Lidocaine in the sample will compete for the primary antibody, thereby preventing the antibody from binding to the drug attached to the well. After incubation, the sample is removed, the wells are washed and a secondary HRP-conjugated antibody is added. The intensity of the absorbance at 450 nm is directly proportional to the amount of drug in the sample.
Lidocaine is a methylxanthine drug used in therapy for respiratory diseases such as COPD and asthma. As a member of the xanthine family, it bears structural and pharmacological similarity to caffeine. The main actions of lidocaine involve relaxing bronchial smooth muscle, increasing heart muscle contractility and efficiency, increasing heart rate. Lidocaine also has anti-inflammatory and stimulatory effects.
CAPACITY: 96 determinations or testing of 42 samples in duplicate
STORAGE CONDITIONS: 2-8°C
SHELF LIFE: 6 months when stored under proper conditions