Bioo Scientific Launches BRCA1/2 Amplicon Panel for Detection of Somatic Mutations in FFPE Samples
$550,000 Awarded to Bioo Scientific to Enable the Improvement of Single Cell Sequencing Technologies
Bioo Scientific Granted Patent for Small RNA Sequencing Technology
Bioo Scientific’s Cell Free DNA-Seq Tech Now Manufactured under ISO 13485
Bioo Scientific Launches Completely Gel-Free or Low Input Small RNA Library Prep Kit
Bioo Scientific Releases Low-input, High Multiplexing Library Prep Solution for SeqCap Target Capture
Bioo Scientific Showcases Solutions Designed to Improve Exome Capture at ASHG 2015
Bioo Scientific Releases Automated Small RNA Library Prep Protocol for the Sciclone NGS Workstation
Bioo Scientific Increases Multiplexing Capabilities for Illumina Sequencing with >2,000 Single-Index Barcodes
Bioo Scientific Releases Automated NEXTflex Protocols for the Sciclone NGS Workstation
Bioo Scientific Releases Complete Library Prep Combo Kit to Improve SureSelectXT2 Target Capture
Bioo Scientific Partners with the Icahn School of Medicine at Mount Sinai to Reduce Ligation Bias in Next Generation Sequencing
Bioo Scientific Launches Kit Offering Robust, Automation-friendly cfDNA Isolation
What's Next in NGS Blog
DETECT GERMLINE MUTATIONS IN LEP, LEPR, POMC, AND MC4R GENES WITH THE NEXTFLEX OBESITY-1 AMPLICON PANEL
The NEXTflex™ Obesity-1 Amplicon Panel offers 100% coverage of the 26 coding exons of the LEP, LEPR, POMC, and MC4R loci and flanking intron-exon boundaries with 100% uniformity of amplicons at 0.2X mean coverage. A complete solution for targeted sequencing, including gene specific primers, PCR Master Mix, clean-up beads, and up to 384 barcodes, the NEXTflex Obesity-1 Amplicon Panel requires only 20 ng of genomic DNA isolated from fresh or frozen samples.
COMPLETE, VALIDATED SOLUTION TO DETECT MEFV GERMLINE MUTATIONS
The NEXTflex™ Mediterranean Fever Amplicon Panel allows you to quickly target and sequence 11 exons of the MEFV loci for the detection of germline mutations. Familial Mediterranean Fever (FMF), associated with mutations in the MEFV gene, is the most common autoinflammatory disease. The mutations in MEFV result in uncontrolled production of interleukin 1, and inflammation. 300 allelic variants of MEFV have been described, with nine considered to be pathological variants with various significance.
MULTIPLEXING BARCODES WITH DIFFERENT INDEX LENGTHS IN A SINGLE RUN
Occasionally, it may be necessary to combine libraries that have different length indexes into a single sequencing run. Using the NEXTflex™ Barcodes, barcodes with indexes of 6-12 nucleotide length can be combined into a single run by lengthening the shorter barcodes to the length of the longest.
BISULFITE SEQUENCING OVERVIEW
The NEXTflex™ Bisulfite-Seq Kit uses a similar workflow to other DNA-Seq library preparation kits, but with the addition of a bisulfite conversion step. This conversion takes place following adapter ligation, and consists of denaturing and chemically converting all non-methylated cytosines into uracils.
BRCA1/2 Amplicon Panel Offers Best-in-class Performance for Detection of Mutations in FFPE Samples
The NEXTflex™ BRCA1 and BRCA2 Amplicon Panel for FFPE lllumina Sequencing can be used to detect clinically relevant somatic mutations in DNA isolated from FFPE samples, to facilitate variant discovery and confirmation. This kit is a cost-effective, optimized solution offering best-in-class performance for on-target percentage and coverage uniformity.
Bioo Scientific’s NGS Marketing Collateral Places in Top International Award
Out of more than 5,000 submissions from 21 countries, Bioo Scientific is named a Silver winner in the 2016 Summit Creative Award® competition for its 2016 NGS Calendar which was entered in the Specialty Item category.