Rapid Metagenomic Diagnostics for Suspected Outbreak of Severe Pneumonia

Volume 20 EID CDC



Researchers from the University Medical Centre Hamburg–Eppendorf, the German Center for Infection Research, and the Heinrich Pette Institute Leibniz Institute for Experimental Virology used the NEXTflex™ ChIP-Seq Kit and NEXTflex™ ChIP-Seq Barcodes in a clinical diagnostic setting to identify the etiologic agent of a suspected pneumonia outbreak among German police officers. Nucleic acids were extracted from bronchoalveolar lavage (BAL) specimens from two patients and used in next generation sequencing. The pneumonia cases were found to result from different etiologic agents and were not part of a larger outbreak.

Fischer, N., et al. (2014) Rapid metagenomic diagnostics for suspected outbreak of severe pneumonia [letter]. Emerg Infect Dis. doi: 10.3201/eid2006.131526.

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