Catalog #: 3604
CD4 V1 Domain Antibody Conjugated to Protamine

CD4 is a glycoprotein that is expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages and dendritic cells.  CD4, together with the T cell receptor, recognizes MHC class II molecules.  CD4 cell counts are used as indicator of AIDS progression.  In addition to virus binding, CD4 may have an active role in membrane fusion.

References:  Healey D et al. 1990. J. Exp. Med. 172(4):1233-1242.

                   Dornan S et al. 2002. J. Biol. Chem. 277(3):1912-8.